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Movie Review: Love and Other Drugs
cogamist

Love and Other Drugs *** ½
Directed By:
Edward Zwick.
Written By: Charles Randolph & Edward Zwick & Marshall Herskovitz based on the book by Jamie Reidy.
Starring: Jake Gyllenhaal (Jamie Randall), Anne Hathaway (Maggie Murdock), Oliver Platt (Bruce Winston), Hank Azaria (Dr. Stan Knight), Josh Gad (Josh Randall), Gabriel Macht (Trey Hannigan), Judy Greer (Cindy), George Segal (Dr. James Randall), Jill Clayburgh (Nancy Randall), Kate Jennings Grant (Gina), Katheryn Winnick ('Lisa'), Kimberly Scott (Gail).

Sometimes a director needs to step out of their comfort zone to do some of their best work. Such is the case with Edward Zwick and his latest film Love and Other Drugs. While the film is certainly flawed, when the film works, and most of it does, it is the type of intelligent, warm and funny romantic comedy we don’t see much anymore. Most of Zwick’s films are burdened by their own importance – whether it be his WWII film Defiance, his African set Blood Diamond, his Japanese set The Last Samurai, or his terrorism drama The Siege, his films often try too hard to be seen as “important” to really work as well as they should. In Love and Other Drugs, Zwick’s directorial style is much more relaxed – he doesn’t force anything, he just lets it play out naturally. Yes, there are elements of the film that don’t work as well as perhaps they should – but the center of the film works like a dream.

Jake Gyllenhaal plays Jamie Randall, the “black sheep” of his family of medical professionals. His father was a doctor, and now teaches medicine. His sister is a doctor. His brother Josh (Josh Gad) invented a medical software company that he sold and became an instant millionaire at a young age. But when we meet Jamie, he is selling stereo equipment. He is a good salesman – effortless and charming – and his brother gets him a job at Pfizer as a medicine salesman. Essentially his job is to go around to doctors and get them to prescribe Pfizer’s drug instead of his competitions. He struggles a bit when he tries to convince doctors to prescribe Zoloft instead of Prozac – but when Pfizer introduces online pharmacy viagra he becomes a rock star salesman. Of course, Viagra pretty much sells itself, doesn’t it?

This view of the medical profession is interesting in its own right, but not enough to sustain a movie – especially since I cannot quite tell if Zwick and company think that what Jamie is doing is right or wrong. Yes, he is helping people get on medication they need – but shouldn’t doctors be prescribing patients drugs on the basis of their needs, instead of what drug reps tell them?

But luckily, this is only part of the movie – the less interesting part. What drives the movie is the relationship that Jamie develops with Maggie (Anne Hathaway). He first meets Maggie while on rounds with a doctor (Hank Azaria), where he is posing as an “intern” to try and get close to the doctor. She discovers his secret – and is pissed (she had removed her top in the exam room), but gradually he wins her over. She has early onset Parkinson’s disease and has done a good job at keeping everyone away from her – she forms no emotionally attachments, because they are too painful. Jamie is the same way, so they bond quickly over sex. It’s only gradually that emotions, and love, start to form between them – much to the chagrin of both of them.

This part of the movie – and it does represent most of the movie – is what works so well about the film. True, to a certain extent, Jamie’s “journey” in the film is similar to many men in recent romantic comedies – immature guy meets the girl of his dreams and grows up – but it feels natural in this movie. Gyllenhaal is a naturally charming actor, and he does the salesman part of his role extremely well, and he navigates the emotionally part with humor and warmth as well. But it is Hathaway who pretty much steals the movie. She is brilliant in it – funny, sweet, kind, intelligent, yet with a nasty streak in her as well, which she grows frustrated about her disease. This isn’t the typical saintly sick person we see in the movie – her Parkinson’s is early enough that it hardly feels like a sick person role at all – and Hathaway delivers one of her best performances.

Love and Other Drugs at times ventures too far into sitcom territory – usually when Jamie’s brother is involved. Josh Gad is amusing and at times quite funny in his role – but it is better suited in a sitcom than a feature film like this. At times, he almost seems to derail the movie with his role. There are a few other moments like that, which perhaps shows Zwick’s rust when doing material like this, since he has spent so long on those “important” dramas. But they are minor flaws, not fatal ones.

Love and Other Drugs is the type of romantic comedy-drama that we rarely see anymore. It is do with humor, warmth and intelligence, and in its two leads, Hathaway in particular; they have found two great characters whose relationship feels genuine. There are flaws in the film sure – but I wouldn’t write the movie, which for so much of its running time works so well, because of them. Love and Other Drugs is funny, sweet, sad and intelligent. How many other movies can you say that about?


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cogamist

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Mark,

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Premature ejaculation: definition, assessment and management
cogamist
Premature ejaculation can be a distressing condition for men and their partners. Premature, early or rapid ejaculation are all terms used to describe the event whereby men are unable to control ejaculation during sexual arousal and/or activity. The control of ejaculation is thought to be related to changes in serotonin and dopaminergic neurotransmission,1 specifically 5-hydroxytryptamine (5-HT)2C receptor hyposensitivity and/or 5-HT1A receptor hypersensitivity, but the precise mechanism controlling ejaculation has yet to be determined.
Recently, premature ejaculation (PE) has become characterised by ejaculating within few minute or before partner or self-satisfaction. The time between vaginal penetration and ejaculation is referred to as intra-vaginal ejaculatory latency time (IELT), although ejaculatory latency time (ELT) may be a more appropriate term as it acknowledges other forms of sexual activity. Normal ejaculatory latency has been cited as being six to thirteen minutes after vaginal penetration.
Definition - PE has been defined as persistent ejaculation with minimal stimulation, which is not a result of withdrawal of opiates, and that results in marked distress. This definition assumes regular sexual activity with the same person for around six months. Some definitions - inability to delay ejaculation (no self controle) on all or most vaginal penetrations; and negative consequences (eg distress, bother, guilt / depression, avoidance of intimacy).
The prevalence of PE:- Based on epidemiological data, PEis estimated to be 22.7 per cent, which is higher than the estimated prevalence of erectile cheap viagra.
The causes of PE are not precisely known. This is due partly to the different types of PE and partly to a lack of consensus on definition. There are four proposed types of PE. Lifelong PE is thought to be caused by neurobiological or genetic factors, whereas acquired PE might be caused by hormonal or vitamin deficiency, poor neurological co-ordination, infection, withdrawal of opiates, performance anxiety or other psychosexual or relationship concerns. The remaining categories are not thought to have any biological causation.
Type of premature ejaculation: 1- Lifelong. 2- Acquired. 3- Natural variable. 4- Situational.
The nature of the problem needs to be established, as PE may be caused by prostatitis (more commonly subclinical prostatitis), necessitating an examination of the prostate on USG. It is also essential to know what the patient wants out of the consultation, as some men expect sexual activity to be mutually orgasmic and have unrealistic expectations of normal ejaculatory latency. If the prostate is tender on examination, treatment with 500mg ciprofloxacin twice daily for four weeks may resolve the problem. It is also important to determine whether the man has erectile cheap cialis rather than PE.
No further examinations are needed, although the opportunity can be taken to look at testosterone, lipid and glucose levels.
Treatment of premature ejaculation
The most common treatment options for PE are treatment of basic cause that is leading to PE. Behavioural therapies; local anaesthetics, and selective serotonin reuptake inhibitors (SSRIs) or equivalent medication. Phospho-diesterase type 5 inhibitors (PDE5Is) have been used, but their precise mechanism of action is unclear.
A man who fears that he will lose an erection before ejaculating may well increase the speed of intercourse, thus giving himself PE. The underlying problem in these circumstances is loss of tumescence related to the narrowing of the pudendal artery, in which case a PDE5I may be a more appropriate prescription.
While SSRIs have not been found to maintain ejaculatory delay in all men after cessation of treatment, some with acquired PE have been able to sustain ejaculatory delay. Where possible, appointments should involve both partners, as the solution involves a couple rather than a solitary approach.
Sensate focus
Each couple will have their own ‘rules’ for sexual activity and intimacy, and negative feelings, eg pressure to perform, tiredness, pain, upset, guilt or worry, can affect both partners' desire for sexual activity. These feelings need to be articulated and discussed for PE to resolve. If the relationship has deteriorated to the point where no intimacy is present, or where no sexual activity is attempted, relationship counselling rather than sex therapy is needed. Behavioural therapy, Squeeze technique, Stop/start technique have their limitations. Kegal exercise helps.
New treatments
Recently, two further treatments have been investigated, with promising results:
topical eutectic mixture for PE (TEMPE)27 – an aerosol delivery of lidocaine-prilocaine;
dapoxetine – a serotonin transport inhibitor and the first SSRI licensed for treatment of PE.The potential advantages of dapoxetine are that it is a short-acting SSRI with few side-effects. It has been found to be effective on first dose, rather than after seven to ten days, as with other SSRIs.
The choice of whether to start medication or refer to a sex therapist can be difficult. A two-month course may be sufficient to help alleviate the pressure on men to perform in their sexual relationships. At the end of two months, a re-assessment of whether the man has been able to delay and control ejaculation can be undertaken. If there is no improvement, alternative pharmacological therapies and sex therapy may help.
PREMATURE EJACULATION TIPS
Oil massage or Inject-able preparation do not help in PE. Treatment and medicines do not cost more, Vigra and other preparations are not used for PE(used for ED).. Over counter preparations should not be taken..
New advances n treatment of premature ejaculation has taken place in India. Drug which was available in USA, also approved by US FDA, is available in India now......
It is very effective , safe, and improve performance significantly. Get your sexologist opinion today.
Dr Deshmukh MD Sexologist & Psychiatrist
9923291312

Off and Stumbling
cogamist
It's a new year. We arrived January 5, ready to take the world by the tail and shake it. Little did we know that with Mercury in retrograde (whatever the hell that means), EVERYTHING having to do with the technology we depend on is so crawling with bugs we might as well have taken another couple of weeks off! For the first few days, I blamed it all on Kelly, our new Jr. Associate. But after a week and a half of one step forward, three back, I'm ready to chuck all of our computers and go back to clay cialis. Email? Yeah sure... Just try to get out to the cyberworld without having to re-boot three times a day. Website? Why not have ALL of the portfolio imagery just randomly rearrange itself? THAT would be great. Don't worry about our internal database. Who needs estimates, contacts, invoices or any info on stock imagery? Oh yeah, don't count on surfing any site that gets over 3 visitors a day, 'cause your browser(s) will just spin and spin. It's not the web hosting company's fault. It's not the phone company's. Apple's? The modem? Router? Nah... It's Mercury's. I'm sure of it now.

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